UCLA researchers created a single-cell map of the developing human neocortex in Down syndrome during a critical window of ...

A cellular-resolution map of prenatal brain development in Down syndrome reveals disrupted neuron production timing and altered cell types.

Scientists mapped human brain development in Down syndrome at a cellular level, discovering that stem cells "rush" to become ...

UCLA scientists have produced one of the first high-resolution molecular maps showing how Down syndrome disrupts human brain development before birth. The study analyzed over 100,000 nuclei from ...

Two major studies have mapped how Down syndrome reshapes brain development before birth and traced the genetic evolution of a rare leukemia affecting children with the condition. UCLA researchers ...

In a bid to better understand, and potentially treat, a host of conditions that affect early cognition, neurodevelopment, and the brain later in life, investigators at Johns Hopkins Medicine and ...

The image shows how different elements of the genome are used during the birth of neurons in the mouse (left), monkey (center) and human (right) brain. Each tiny dot is a single cell in the developing ...

The human brain's advanced cognitive capabilities are often attributed to our recently evolved neocortex. Comparison of human and rodent brains shows that the human cortex is thicker, contains more ...

Scientists at UCLA have created one of the first cellular-resolution molecular maps detailing how Down syndrome alters human ...